Liver function

Overview

Research suggests an inverse association between moderate coffee consumption and the risk of developing a range of liver diseases including cancer, fibrosis, cirrhosis and non-alcoholic fatty liver disease (NAFLD).

Background information

The European Association for the Study of the Liver estimates that approximately 29 million people in the European Union suffer from a chronic liver condition31 and that mortality attributable to liver diseases has risen four-fold between 1970 and 2013.

Latest research

Liver function

PNPLA3 rs738409, environmental factors and liver-related mortality in the U.S. Population

E Vilar-Gomez et al, 2024. PNPLA3 rs738409, environmental factors and liver-related mortality in the U.S. Population, Journal of Hepatology.

October 16, 2024

Liver function

Diabetes risk reduction diet and risk of liver cancer and chronic liver disease mortality: A prospective cohort study

Y Chen et al, 2024. Diabetes risk reduction diet and risk of liver cancer and chronic liver disease mortality: A prospective cohort study, Journal of Internal Medicine.

September 15, 2024

Liver function

Causal Effects of Smoking, Alcohol Consumption, and Coffee Intake on Hepatobiliary and Pancreatic Diseases: A Mendelian Randomization Study

B Zhao et al, 2024. Causal Effects of Smoking, Alcohol Consumption, and Coffee Intake on Hepatobiliary and Pancreatic Diseases: A Mendelian Randomization Study, Clinics and Research in Hepatology and Gastroenterology.

August 21, 2024

Affects of coffee consumption

Coffee consumption and liver function

Potential mechanisms

References

Latest information campaigns

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Liver function

Liver function factsheet

Liver disease is estimated to affect 6% of the global population (approx. 29 million people) and is reported to be the 14th most prevalent cancer and 5th biggest killer in Europe.

Factsheets

November 11, 2019

Liver function

Liver function factsheet

Liver disease is estimated to affect 6% of the global population (approx. 29 million people) and is reported to be the 14th most prevalent cancer and 5th biggest killer in Europe.

Factsheets

November 11, 2019

Liver function

Looking after the liver: lifestyle, coffee and caffeine

Liver disease encompasses a number of conditions including hepatitis, cirrhosis, non-alcoholic fatty liver disease, and hepatocellular cancer. A modern lifestyle, often with excess intakes of alcohol, calories and fat is associated with an increase in the incidence of liver disease.

Reports

November 15, 2017

Liver function

Looking after the liver: lifestyle, coffee and caffeine

Liver disease encompasses a number of conditions including hepatitis, cirrhosis, non-alcoholic fatty liver disease, and hepatocellular cancer. A modern lifestyle, often with excess intakes of alcohol, calories and fat is associated with an increase in the incidence of liver disease.

Reports

November 15, 2017

Liver function

Coffee and liver function – an overview of research

This short animated presentation summarises the existing body of research around coffee consumption and liver function. Click to view, and feel free to share with colleagues.

Video/audio

December 17, 2014

Liver function

Coffee and liver function – an overview of research

This short animated presentation summarises the existing body of research around coffee consumption and liver function. Click to view, and feel free to share with colleagues.

Video/audio

December 17, 2014

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