ABSTRACT

Coffee consumption is a prevalent daily practice worldwide, and coffee is known to contain a variety of chemical compounds that can impact human health. This study aims to examine the influence of coffee consumption on serum lipid profile. To achieve this, a total of 109 participants from the Jordanian population were recruited for this study, spanning from April 2022 to September 2022. Of these, 90 individuals were regular coffee consumers, while 19 individuals served as a healthy control group by abstaining from coffee consumption. Venous blood samples were collected from participants and subjected to serum lipid profile analysis using an automated biochemistry analyzer. The results indicated no statistically significant differences in age (48 ± 6 years vs. 45 ± 7 years) and body mass index (27.9 ± 5.9 kg/m2 vs. 27.3 ± 5.2 kg/m2 ) between the group of coffee consumers and the non-coffee consuming control group. However, a significant increase was observed in the mean serum lipid levels of triglycerides (229.6 ± 7.87 mg/dL vs. 187.6 ± 5.43 mg/dL), total cholesterol (235.9 ± 17.83 mg/ dL vs. 228 ± 8.75 mg/dL), low-density lipoprotein cholesterol (144.6 ± 5.97 mg/dL vs. 137.8 ± 7.18 mg/dL), and very low-density lipoprotein cholesterol (45.8 ± 1.58 mg/dL vs. 37.5 ± 1.43 mg/dL) in the coffee[1]consuming group compared to the non-coffee consuming group (p < 0.05). Additionally, it was observed that the serum total cholesterol level in Turkish coffee consumers (235.7 ± 17.83 mg/dL) was lower compared to instant coffee consumers (237 ± 6.82 mg/dL) (p < 0.05). This study also found that serum lipid abnormalities in the coffee-consuming group is associated with the frequency and the long-term coffee consumption. In conclusion, this study suggests that coffee consumption may elevate the risk of serum lipid abnormalities among adults in Jordan, potentially increasing the susceptibility to cardiovascular diseases.