Serum amyloid A is a type of lipoprotein that may be associated with chronic inflammation in the body.
- A 2010 Finnish study tested the effects of progressively increasing coffee consumption in obese volunteers in a medium term intervention trial (month one = abstention; month two = 4 cups of coffee per day; month three = 8 cups per day). No effects in the OGTT were seen. Coffee consumption appeared to have beneficial effects on some markers of subclinical inflammation, considered to be risk factors for type 2 diabetes13
- A 2015 Greek study, which controlled for oxidative stress and inflammatory biomarkers, suggested that the inverse association between habitual coffee drinking and diabetes was found to be mediated by serum amyloid A levels14