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Potential mechanisms

The precise mechanisms to explain the suggested association between coffee consumption and reduced overall mortality risk are currently unknown, and research is ongoing to understand this area in more detail.

However, a number of hypotheses exist and have considered roles for specific coffee constituents, including caffeine, cafestol and kahweol, as well as some of the phyto-chemicals found in coffee^1,8,11,12.

Coffee consumption and disease specific mortality

References

Potential mechanisms

Latest research

Habitual Coffee Consumption and Risk of Cardiovascular Disease and All-Cause Mortality in the PAMELA Hypertensive Population

F Quarti-Trevano et al, 2024. Habitual Coffee Consumption and Risk of Cardiovascular Disease and All-Cause Mortality in the PAMELA Hypertensive Population, Nutrition, Metabolism & Cardiovascular Disease.

Relationship between timing of coffee and tea consumption with mortality (total, cardiovascular disease and diabetes) in people with diabetes: the U.S. National Health and Nutrition Examination Survey, 2003-2014

R Yang et al, 2024. Relationship between timing of coffee and tea consumption with mortality (total, cardiovascular disease and diabetes) in people with diabetes: the U.S. National Health and Nutrition Examination Survey, 2003-2014. BMC Med.

Association of caffeine consumption with all-cause and cause-specific mortality in adult Americans with hypertension

K Wang et al, 2024. Association of caffeine consumption with all-cause and cause-specific mortality in adult Americans with hypertension, Food Science and Nutrition.

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Coffee, caffeine, mortality and life expectancy

Coffee, caffeine, mortality and life expectancy